Kappa opioid receptor (KOR) modulation of dopamine in the cortex and... | Download Scientific Diagram
![Nephrology Journal Club on X: "Difelikefalin (CR845) (KORSUVA) is a peripherally restricted, selective kappa opioid receptor agonist that exerts antipruritic effects by means of activation of kappa opioid receptors on peripheral neurons Nephrology Journal Club on X: "Difelikefalin (CR845) (KORSUVA) is a peripherally restricted, selective kappa opioid receptor agonist that exerts antipruritic effects by means of activation of kappa opioid receptors on peripheral neurons](https://pbs.twimg.com/media/EJQpY99U4AY2hKN.jpg)
Nephrology Journal Club on X: "Difelikefalin (CR845) (KORSUVA) is a peripherally restricted, selective kappa opioid receptor agonist that exerts antipruritic effects by means of activation of kappa opioid receptors on peripheral neurons
![Representative examples of common scaffolds in kappa opioid receptor... | Download Scientific Diagram Representative examples of common scaffolds in kappa opioid receptor... | Download Scientific Diagram](https://www.researchgate.net/publication/319055003/figure/fig2/AS:658264614256644@1533953922774/Representative-examples-of-common-scaffolds-in-kappa-opioid-receptor-ligands.png)
Representative examples of common scaffolds in kappa opioid receptor... | Download Scientific Diagram
![Discovery and Binding Mechanism of Pyrazoloisoquinoline-Based Novel β-Arrestin Inverse Agonists of the Kappa-Opioid Receptor | Journal of Medicinal Chemistry Discovery and Binding Mechanism of Pyrazoloisoquinoline-Based Novel β-Arrestin Inverse Agonists of the Kappa-Opioid Receptor | Journal of Medicinal Chemistry](https://pubs.acs.org/cms/10.1021/acs.jmedchem.3c00064/asset/images/medium/jm3c00064_0011.gif)
Discovery and Binding Mechanism of Pyrazoloisoquinoline-Based Novel β-Arrestin Inverse Agonists of the Kappa-Opioid Receptor | Journal of Medicinal Chemistry
Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical Neuroscience
![Molecules | Free Full-Text | Development of Diphenethylamines as Selective Kappa Opioid Receptor Ligands and Their Pharmacological Activities Molecules | Free Full-Text | Development of Diphenethylamines as Selective Kappa Opioid Receptor Ligands and Their Pharmacological Activities](https://www.mdpi.com/molecules/molecules-25-05092/article_deploy/html/images/molecules-25-05092-g001.png)
Molecules | Free Full-Text | Development of Diphenethylamines as Selective Kappa Opioid Receptor Ligands and Their Pharmacological Activities
![Structure-Based Discovery of New Antagonist and Biased Agonist Chemotypes for the Kappa Opioid Receptor | Journal of Medicinal Chemistry Structure-Based Discovery of New Antagonist and Biased Agonist Chemotypes for the Kappa Opioid Receptor | Journal of Medicinal Chemistry](https://pubs.acs.org/cms/10.1021/acs.jmedchem.7b00109/asset/images/large/jm-2017-00109c_0010.jpeg)
Structure-Based Discovery of New Antagonist and Biased Agonist Chemotypes for the Kappa Opioid Receptor | Journal of Medicinal Chemistry
![Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria | Science Signaling Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria | Science Signaling](https://www.science.org/cms/asset/35d59cc9-5e24-4990-b0eb-4fc248e3274c/9_ra117_f1.gif)
Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria | Science Signaling
![Frontiers | A Review of the Therapeutic Potential of Recently Developed G Protein-Biased Kappa Agonists Frontiers | A Review of the Therapeutic Potential of Recently Developed G Protein-Biased Kappa Agonists](https://www.frontiersin.org/files/Articles/447554/fphar-10-00407-HTML/image_m/fphar-10-00407-g002.jpg)
Frontiers | A Review of the Therapeutic Potential of Recently Developed G Protein-Biased Kappa Agonists
![Molecules | Free Full-Text | Design of κ-Opioid Receptor Agonists for the Development of Potential Treatments of Pain with Reduced Side Effects Molecules | Free Full-Text | Design of κ-Opioid Receptor Agonists for the Development of Potential Treatments of Pain with Reduced Side Effects](https://pub.mdpi-res.com/molecules/molecules-28-00346/article_deploy/html/images/molecules-28-00346-g007.png?1672561695)
Molecules | Free Full-Text | Design of κ-Opioid Receptor Agonists for the Development of Potential Treatments of Pain with Reduced Side Effects
![Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical Neuroscience Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical Neuroscience](https://pubs.acs.org/cms/10.1021/cn200128x/asset/images/large/cn-2011-00128x_0006.jpeg)
Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical Neuroscience
![A unique natural selective kappa-opioid receptor agonist, salvinorin A, and its roles in human therapeutics - ScienceDirect A unique natural selective kappa-opioid receptor agonist, salvinorin A, and its roles in human therapeutics - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0031942217300420-fx1.jpg)